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BEGIN:VEVENT
UID:782560426e35d648d00acd007cfc7542
DTSTAMP:20260614T224950Z
SUMMARY:Multistage Optimal Transport evaluated on scRNA-seq Human Bone Marr
 ow data
DESCRIPTION:Contact: anders.rantzer@control.lth.se\n\nTitle:&nbsp\; Multist
 age&nbsp\;Optimal Transport evaluated on scRNA-seq Human Bone Marrow dataA
 uthor:&nbsp\;Vilhelm Conradi &amp\; Hugo NelssonDate &amp\; Time:&nbsp\;Ju
 ne 4th\, 11:00–11:30Location:&nbsp\;Seminar Room M 3170-73 in the M-buil
 ding\, LTHSupervisor: Anders Rantzer and&nbsp\;Karl RydénExaminer:&nbsp\;
  Magnus FontesAbstract:With novel techniques like single cell RNA sequenci
 ng we can look inside single cells in great detail and count the amounts o
 f individual genes present in them. When modeling differentiation of cells
  one typically would use longitudinal data but assuming that every cell st
 ate in the differentiation process is present in one cell sample we presum
 e that we have sufficient information to model the differentiation process
  from snapshot data. Building on the assumption that cell states similar t
 o each other are closer in the space defined by their genes\, and that nat
 ure would take the path through the gene space with the smallest cost\, we
  use a newly proposed optimal transport algorithm to find differentiation 
 trajectories through bone marrow samples and order cell adhering to Hemato
 poiesis in pseudotime. We then extract lists of genes describing these tra
 jectories and evaluate their function to asses the viability of the new op
 timal transport algorithm. The ambition is that this method can aid the st
 udy of the development of Acute Myeloid Leukemia\n\nMore information about
  the event: https://www.control.lth.se/calendar/multistage-optimal-transpo
 rt-evaluated-scrna-seq-human-bone-marrow-data
DTSTART;TZID=GMT:20260604T090000
DTEND;TZID=GMT:20260604T093000
LOCATION:Seminar Room M 3170-73 in the M-building\, LTH
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